Silymarin occurs in milk thistle fruit and seeds, and helps shield skin from the visible effects of UV light exposure (of course, you still need a broad spectrum sunscreen). There is insufficient evidence to support the use of milk thistle for any of the below listed uses. Milk thistle can also be used to prevent the complications of cirrhosis such as hepatic failure, and liver carcinoma. Read on to learn more about what milk thistle is, its supposed benefits, and the side effects and safety of Silybum marianum. The active complex of this herb is a lipophilic extract obtained from the seeds of the plant. A European standardized extract of milk thistle was used in most of the trials. Secondary effects? [where?] Does Sunscreen Application Affect Vitamin D Formation? Silybum Marianum Health Benefits Silybum marianum is used to treat dyspepsia (heartburn), and is especially effective when used in combination with other plant extracts, such as lemon balm, angelica, peppermint and chamomile. Antioxidant, anti-inflammatory, anticarcinogenic, hepatoprotective, immunostimulating, possibly estrogenic. Milk thistle (Silybum marianum) is a thorny plant presenting decorative leaves with a white pattern of veins and purple flower heads.The plant originates from mountains of the Mediterranean region, where it forms scrub on a rocky base. Liver disease. Protecting the liver when taking strong drugs or medicine. Silybum marianum is the more technical name for milk thistle. Silymarin also seems to encourage liver cell growth. Milk thistle (Silybum marianum) is a flowering herb known for its important medicinal properties. Gaertn.) viral hepatitis ) and the extract, silymarin , is used in medicine. The aim of this study was to investigate the molecular mechanisms of the efficacy of lignin compound dehydrodiconiferyl alcohol (DHCA) isolated from Silybum marianum (L.) Gaertn in improving wound healing. Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biological effect.It is used in different liver disorders, particularly chronic liver diseases, cirrhosis and hepatocellular carcinoma, because of its antioxidant, anti-inflammatory and antifibrotic power. More about Milk Thistle in history Silybum marianum is a familiar thorny plant that’s prickly leaves contain splashes of white, which were historically referred to … The extract of this herb is used to reap its cell regenerating benefits. Mediterranean regions, Meadows, Borders of forests. Cirrhosis is characterized by scarring and permanent, non-reversible damage to the liver. It also helps to inhibit the free radical chain reaction mechanism. The efficacy of Silibin present in this herb against the human hepatocellular carcinoma cells was studied. As the disease progresses, hepatic failure may set in. Mediterranean region. Milk Thistle also acts as a toxin blockade agent and inhibits the binding of toxins to the cell membrane receptors on the hepatic cells. Uses and Health Benefits of Silybum Marianum Helps protect against cancer Although more studies on Mary thistle’s effects on cancer are still in early stages, it appears that this plant extract can have an inhibitory effect on the expansion of cancer cells and tumors on the skin and can also help prevent cancerous growth in the breast, prostate, and cervix. Do not take carduus marianum, holy thistle, lady's thistle, legalon, Marian thistle, Mary thistle, silibinin, silybin, silybum marianum, silymarin, or St Mary thistle if you are allergic to milk thistle or any ingredients contained in this drug. Milk thistle (Silybum marianum L. The effect of Silibinin on the growth, apoptosis, cytotoxicity, and cell cycle progression was examined in two HCC cell lines, Hep3B (hepatitis B virus positive with p53 mutated) and HepG2 (hepatitis B virus negative with p53 intact). How Celery Can Lower Your Uric Acid Levels? At the end of the research, nine patients were tested negative for HCV-RNA. The results of this study indicated that Silibinin could strongly inhibit the growth of HepG2 and Hep3B cells. Milk thistle was approved in 1986 as a treatment for liver disease and it is widely used to treat alcoholic hepatitis, alcoholic fatty liver, cirrhosis, liver poisoning and viral hepatitis. In the middle ages, the leaves were used in salads, but these days … It acts as a powerful detoxifier and helps to rebuild the liver cells. The results of this study showed a statistically significant difference in the mean ALT and AST levels before and after the treatment. Antioxidants are thought to protect body cells from damage caused by a chemical process called oxidation. Always take care when taking herbs and Read Our Disclaimer. Indigestion (dyspepsia). The anti-cancer potential of Milk Thistle was evaluated during research. It has been used for thousands of years as a herbal remedy for a variety of ailments, particularly for the liver. Psoriasis. It was found that Silymarin obtained from Milk Thistle could improve the liver functions in the patients infected with the hepatitis C virus. Our Milk Thistle is not standardized to an exact amount (as it is made from pure dried natural herbs. It may also be used to start late menstrual periods. that the active flavanoid-lignan (flavanolignan) group of constituents, called silymarin, contained only in the seed shell has liver-protective and regenerative properties, as well as antioxidant effects. The G1 arrest was found to be induced in the HepG2. ... [Effect of Silybum marianum oil and legalon on lipid peroxidation and liver antioxidant systems in rats intoxicated with carbon tetrachloride]. In animal studies and one small study in humans, milk thistle produced modest reductions in total cholesterol. Known sometimes as Mary thistle or holy thistle, and scientifically as Silybum marianum, milk thistle is a flowering plant originally from the Mediterranean region, although it has been brought to other regions, including North America. Men who have prostate cancer should not take milk thistle without the approval of a doctor. Silymarin in Milk Thistle also produces an antifibrotic activity. Milk Thistle is unique in its ability to protect the liver and has no equivalent in the pharmaceutical drug world. Milk thistle, or silybum marianum, has been used as a herbal healer since ancient Greek times. A positive change in the overall quality of the life of patients was also observed. There may also be an enlargement of the liver in the initial stages of cirrhosis. Sylimaryna działa stabilizująco na błony komórkowe komórek wątroby, dzięki czemu chroni wątrobę przed uszkodzeniami. Figure 1. Silybum marianum has other common names including cardus marianus, milk thistle, blessed milkthistle, Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle (though not to be confused with Onopordum acanthium). What is milk thistle? However, these results have not been demonstrated in larger human studies. These findings preliminarily brought to light the promising therapeutic potential of … The anti-angiogenic activity of this herb is evident in the human umbilical vein endothelial cells in a dose-dependent manner. The trial showed that this herb could improve the survival rate of the patients suffering from this disease. It stimulates the enzyme formation in the liver thus restoring its normal functions. is the most researched plant for the treatment of liver disease. It stimulates the enzyme formation, increases the bile production, decreases inflammation, and soothes the mucous membranes. Health Benefits of Milk Thistle. An improvement in the liver fibrosis markers was also noticed. Its therapeutic properties are due to the presence of silymarin, a mixture of three flavonolignans (silybin, silydianin and silycristin). It was also found to exert a relatively stronger cytotoxic effect on the Hep3B cells that was associated with the induction of apoptosis. is the most researched plant for the treatment of liver disease. It also offers a rich source of flavonoids. Our impartial buyers guide lets you know what to look out for to get the best products. The X axis shows three categories of patch types: Green, patch of a green mutant; Var-G, green patch on a variegated leaf; Var-W, white patch on a variegated leaf. Milk Thistle is commonly used in the treatment of liver disorders. The seeds and fruits of SM contain a flavonolignan complex called silymarin, the active compounds of which include silybin, isosilybin, silychristin, dihydrosilybin, silydianin, and so on. Biochemical content of Silybum marianum white and green patches. Cirrhosis is a chronic liver condition that develops due to the formation of a scar tissue in the liver, which replaces the normal, healthy hepatic tissues. However, as the disease progresses the liver shrinks in size. It can reduce inflammation (important for people with liver inflammation or hepatitis), and has potent antioxidant effects. Milk thistle (Silybum marianum) is a relative of dandelion and regular artichoke. What is Milk-Thistle Herb? Milk Thistle helps in treating cancer by producing a cytoprotective activity. It has also been shown to protect the liver against medications such as acetaminophen, a non-aspirin pain reliever. alcoholic fatty liver, liver poisoning. The following purported benefits are only supported by limited, low-quality clinical studies. In Europe, milk thistle is a prescribed medication. It helps in the management of liver disorders by protecting it against the effect of toxins. Medicinal properties? Milk thistle, known as 'Doodh Patra' has medicinal properties. Read on to learn more about what milk thistle is, its supposed benefits, and the side effects and safety of Silybum marianum. In traditional knowledge, people have used S. marianum for liver disorders such as hepatitis, liver cirrhosis and gallbladder diseases. Additionally, Milk Thistle can also help to reduce the risk of diseases that can lead to cirrhosis such as alcoholic hepatitis, viral hepatitis, and toxin-induced liver diseases. It helps to detoxify the body, especially the blood and liver. Silymarin marianum is a plant whose many components, primarily a flavanolignan chemical known as silymarin, have pronounced antioxidant and skin-calming ability. It contains a variety of lignans, including silandrin, silybin, silychristin, silydianin, silymarin, and silymonin. It has been used for thousands of years as a herbal remedy for a variety of ailments, particularly for the liver. ... [Effect of Silybum marianum oil and legalon on lipid peroxidation and liver antioxidant systems in rats intoxicated with carbon tetrachloride]. It contains a variety of lignans, including silandrin, silybin, silychristin, silydianin, silymarin, and silymonin. Milk thistle also contains other important nutrients such as vitamin E and vitamin C. It also contains a high amount of lipophilic compounds that act as a bioflavonoid antioxidant. Some preliminary research has suggested that milk thistle may be as effective as the common medication fluoxetine in the treatment of obsessive-compulsive disorder. Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been widely used to treat various diseases, especially hepatic diseases. Further studies are needed to determine whether milk thistle is safe or effective for people with these forms of cancer. Milk Thistle helps to treat cirrhosis by acting as an anti-inflammatory and hepatoprotective agent. Milk thistle can reduce the effect of toxins and alcohol on the liver. It contains a variety of lignans, including silandrin, silybin, silychristin, silydianin, silymarin, and silymonin. Milk thistle is commonly used as a home remedy to treat liver problems, often under the presumption that it will "detoxify" the liver. Mild gastrointestinal distress is the most common adverse event reported for milk thistle. Read More. Milk thistle, or Silybum marianum, is a plant used to treat liver disease and breastfeeding problems, among others. in Medicinal Plants) is an Ayurvedic Practitioner and Herbalist. Dr. Jagdev Singh (B.A.M.S., M. Sc. Milk thistle, known as 'Doodh Patra' has medicinal properties. In fact, in cases of poisoning with Amanita mushrooms, which destroy the liver, milk thistle is the only treatment option. Gaertn.) Preliminary laboratory studies also suggest that active substances in milk thistle may have anti-cancer effects. Milk Thistle (Silybum marianum) The medicinal use of milk thistle can be traced back thousands of years to the times of the Greek and Roman Empires. It can also help to reduce the symptoms of bacterial hepatitis. By changing the outside layer of liver cells, it also prevents certain toxins from getting inside. 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